Are Polynucleotides The Natural Injectable Challenging Botox for Youthful Skin?

A new skincare treatment, dubbed the “salmon-sperm facial,” is generating a significant buzz as a “natural” alternative to traditional injectables like Botox and fillers. Officially known as polynucleotide treatments, this innovative approach employs small fragments of salmon sperm DNA to rejuvenate the skin, mainly targeting the problematic eye area. Endorsed by celebrities like Jennifer Aniston, polynucleotides are gaining popularity for their potential to boost collagen and elastin production, reduce inflammation, and promote overall skin regeneration.

Experts explain that polynucleotides act as “biostimulators,” encouraging the skin’s natural cellular processes that decline with age. Unlike Botox, which temporarily paralyzes muscles, or fillers that add volume, polynucleotides work at a cellular level to improve skin quality from within. Some experts also highlight that while traditional injectables don’t stimulate collagen production, polynucleotides actively encourage skin cells to produce the essential building blocks for a youthful complexion.

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The treatment involves injecting polynucleotides via a cannula or fine needles, typically requiring a series of three sessions spaced a few weeks apart. While most individuals are suitable candidates, those with fish allergies, vegan lifestyles, or a history of anaphylaxis should avoid it. Downtime is generally minimal, with potential bruising or swelling subsiding within 24-48 hours. A course of treatments can range from £450 to £2,000, with results reportedly lasting six to nine months.

Despite the growing enthusiasm, the treatment faces some skepticism. The FDA in the US has yet to approve polynucleotides, citing the need for more robust scientific studies. Dermatologist experts acknowledge the exciting potential but stresses the importance of high-quality research before widespread adoption as a direct alternative to well-established treatments like Botox and fillers.

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Nevertheless, the global polynucleotides injectable market is projected for significant growth, indicating a rising demand for non-surgical aesthetic treatments. While not yet a direct competitor to the massive Botox and dermal filler markets, polynucleotides represent a promising and increasingly sought-after option for those seeking a more natural and regenerative approach to anti-aging.