In a pioneering study, Unilever scientists, in collaboration with the Microbiome Innovation Centre and the Brain & Behaviour Lab at the University of Liverpool, have discovered a potential connection between the skin microbiome and mental wellbeing. This research offers fresh insights that could redefine the relationship between skincare and psychological Health.

Published in the British Journal of Dermatology on May 27, 2025, the study titled Body-site specific associations between human skin microbiome composition and psychological wellbeing” is the first of its kind to explore how the skin microbiome may influence mental wellness across different areas of the body. While the gut microbiome impact on mental health has been widely studied, this research brings attention to the skin role in the skin-brain connection.

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About the Study:

The study highlights that higher levels of beneficial microbes, particularly Cutibacterium, found on the face and underarms, are associated with lower stress and better mood. Across multiple body sites, an increased presence of Cutibacterium consistently correlated with enhanced psychological wellbeing.

These findings build on Unilever’s long-standing microbiome research, which includes more than 30,000 analysed samples and over 100 patents. This positions the company as one of the leaders in human skin microbiome science data. The insights have already influenced product development across Unilever brands like Pond’s, Dove, Vaseline, and Dermalogica, especially in body washes, deodorants, and beauty products.

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Jason Harcup, Chief R&D Officer for Beauty & Wellbeing at Unilever, noted that this research supports the concept of the skin-brain axis, where skin health and emotional wellbeing are interconnected. He explained that the study’s results reveal how certain skin bacteria, particularly Cutibacterium, can be linked to reduced stress and elevated mood, emphasising that consumers now seek products that support both appearance and mental health.

Funded through a Knowledge Transfer Partnership grant from UK Research and Innovation, this research opens the door to developing skincare products that not only care for the skin but also contribute to mental wellness, paving the way for a more holistic approach to beauty and wellbeing.